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Image Search Results
Journal: The Journal of Neuroscience
Article Title: Long-Distance Axonal Regeneration in the Transected Adult Rat Spinal Cord Is Promoted by Olfactory Ensheathing Glia Transplants
doi: 10.1523/JNEUROSCI.18-10-03803.1998
Figure Lengend Snippet: Regenerating axons crossing the gliotic tissue created at both graft–cord interfaces after EG transplantation.A–E, Consecutive spinal cord sagittal sections showing the interfaces between the rostral cord stump and either SC and EG cables or EG connective tissue bridges. Sections were immunolabeled for GFAP (A), ED1 (B), neurofilament (D), and GAP-43 (E). EG were visualized by Hoechst labeling (C). A portion of the channel, which autofluoresces with the filter used, was retained in C(asterisk). Arrowheads inA, B, D, andE point to the cord–cable interface;arrows in A–E mark the EG-containing connective tissue bridge.F–H, Consecutive spinal cord sections showing the caudal cord–cable interface. Dashed lines(F, G) indicate the interface. Sections were immunolabeled for GFAP (F) and GAP-43 (G). Hoechst-labeled EG (H) are in the same region shown inF. Arrows in G point to GAP-43-labeled fibers crossing the cord–cable interface and in the gliotic tissue. Note the presence of EG in the gliotic tissue of both interfaces (C, H) and in both SC-containing cables and connective tissue bridges (C). Scale bars:A–E, 125 μm;F–H, 90 μm.
Article Snippet: We also used
Techniques: Transplantation Assay, Immunolabeling, Labeling